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Hardwired to attack: Transcriptionally defined amygdala subpopulations play distinct roles in innate social behaviors

Lischinsky, J., Yin, L., Shi, C., Prakash, N., Burke, J., Shekaran, G., Grba, M., Corbin, J.G., Lin, D.

bioRxiv2023 Mar 17. [link]

Antagonistic Neural Circuits Drive Opposing Behaviors towards the Young in Females

Long, M., Yan, R., Yin, L., Sullivan, R., Lin, D.

bioRxiv2023 Mar 13. [link]

Neural dynamics in the limbic system during male social behaviors

Guo, Z., Yin, L., Osakada,T., Lischinsky, J.E., Chien, J., Dai,B., Urtecho, A., Tong, X., Chen, Z.S., Lin, D.

bioRxiv2023 Mar 13. [link]

Neural control of female sexual behaviors

Yin, L., Lin, D.

Hormones and Behavior. 2023 Mar 04. [link]

A genetically encoded sensor measures temporal oxytocin release from different neuronal compartments

Qian, T., Wang, H., Wang, P., Geng, L., Mei, L., Osakada, T., Wang, L., Tang, Y., Kania, A., Grinevich, V., Stoop, R., Lin, D., Luo, M., Li, Y.

Nature Biotechnology. 2023 Jan 02. [link]


 A dedicated hypothalamic ox ytocin circuit controls aversive social learning  

Osakada, T., Yan, R., Jiang Y., Wei, D., Tabuchi, R., Dai B., Wang, X., Zhao, G., Wang, C.X., Tsien, R.W., Mar, A.C., Lin, D.
​bioRxiv. 2022 Dec 15. [link]

Responses and functions of dopamine in nucleus accumbens core during social behaviors

Dai, B., Sun, F., Tong. X., Ding, Y., Kuang, A., Osakada, T., Li, Y., Lin, D.
Cell Reports. 2022 Aug 23. [link]

VMHvllCckar cells dynamically control female sexual behaviors over the reproductive cycle

Yin, L., Hashikawa, K., Hashikawa, Y., Osakada, T., Lischinsky, J.E., Diaz, V., Lin, D.
Neuron. 2022 Jul 26. [lin

Pushing the frontiers: tools for monitoring neurotransmitters and neuromodulators

Wu, Z., Lin, D., Li, Y.
Nature Reviews Neuroscience. 2022 Mar 31. [PDF]


Dopamine release in nucleus accumbens core during social behaviors in mice

Dai, B., Sun, F., Kuang, A., Li, Y., Lin, D. 
​bioRxiv. 2021 Jun 23. [link

Oxytocin neurons enable social transmission of maternal behaviour

Carcea, I., Caraballo, N.L., Marlin, B.J., Ooyama, R., Riceberg, J.S., Mendoza Navarro, J.M., Opendak, M., Diaz, V.E., Schuster, L., Alvarado Torres, M.I., Lethin, H., Ramos, D., Minder, J., Mendoza, S.L., Bair-Marshall, C.J., Samadjopoulos, G.H., Hidema, S., Falkner, A., Lin, D., Mar, A., Wadghiri, Y.Z., Nishimori, K., Kikusui, T., Mogi, K., Sullivan, R.M., Froemke, R.C.
​Nature. 2021 Aug 11. [

Neural circuits of social behaviors: innate yet flexible

Wei, D., Talwar, V., Lin, D.

Neuron. 2021 Mar 10. [PDF]


Next-generation GRAB sensors for monitoring dopaminergic activity in vivo

Sun, F., Zhou, J., Dai, B., Qian, T., Zeng, J., Li, X., Zhuo, Y., Zhang, Y., Wang, Y., Qian, C., Tan, K., Feng, J., Dong, H., Lin, D., Cui, G., Li, Y.

Nature Methods. 2020 Oct 21. [PDF]

Neural mechanisms of aggression across species

Lischinsky, J.E., Lin, D.

Nature Neuroscience. 2020 Oct 12. [PDF]

Posterior amygdala regulates sexual and aggressive behaviors in male mice

Yamaguchi, T., Wei, D., Song, S.C., Lim, B., Tritsch, N.X., Lin, D.

Nature Neuroscience. 2020 July 27. [PDF]

Simple Behavioral Analysis (SimBA) – an open source toolkit for computer classification of complex social behaviors in experimental animals

Nilsson, S., Goodwin, N.L., Choong, J.J., Hwang, S., Wright, H. R., Norville, Z.C., Tong, X., Lin, D., Bentzley, B.S., Eshel, N., McLaughlin, R. J., Golden, S.A.

bioRxiv. 2020 April 21. [PDF]

Hierarchical Representations of Aggression in a Hypothalamic-Midbrain Circuit

Falkner, A., Wei, D., Song, A., Watsek, L. W., Chen, I., Chen, P., Feng, J., Lin, D.

Neuron. 2020 Mar 11. [PDF]

Neural circuits for coping with social defeat

Diaz, V., Lin, D.

Current Opinion in Neurobiology. 2020 Feb. [PDF]


PAG neurons encode a simplified action-selective signal during aggression

Falkner, A., Wei, D., Song, A., Watsek, L. W., Chen, I., Feng, J., Lin, D.

bioRxiv. 2019 Aug 24. [PDF]

A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine

Feng, J., Zhang, C., Lischinsky, J., Jing, M., Zhou, J., Wang, H., Zhang, Y., Dong, A., Wu, Z., Wu, H., Chen, W., Zhang, P., Zou, J., Hires, A., Zhu, J.J., Cui, G., Lin, D., Du, J., Li, Y.

Neuron. 2019 Mar 25. [PDF]

Rapid, biphasic CRF neuronal responses encode positive and negative valence

Kim, J., Lee, S., Fang, Y., Shin, A., Park, S., Hashikawa, K., Bhat, S., Kim, D., Sohn, J.W., Lin, D., Suh, G.S.B.

Nature Neuroscience. 2019 Mar 4. [PDF] [Supplement]

Hypothalamic Control of Conspecific Self-Defense

Wang, L., Talwar, V., Osakada, T., Kuang, A., Guo, Z., Yamaguchi, T., Lin, D.

Cell Reports. 2019 Feb 12. [PDF] [Supplement]





The Neural Mechanisms of Sexually Dimorphic Aggressive Behaviors

Hashikawa, K., Hashikawa, Y., Lischinsky, J.,  Lin, D.

Trends in Genetics. 2018 August 30. [PDF]


A Genetically Encoded Fluorescent Sensor Enables Rapid and Specific Detection of Dopamine in Flies, Fish, and Mice

Sun, F., Zeng, J., Jing, M., Zhou, J., Feng, J., Owen, S. F., Luo, Y., Li, F., Wang, H., Yamaguchi, T., Yong, Z., Gao, Y., Peng, W., Wang, L., Zhang, S.,  Du, J., Lin, D., Xu, M., Kreitzer, A. C., Cui, G., Li, Y.

Cell. 2018 July 12. [PDF] [Supplement]


Functions of medial hypothalamic and mesolimbic dopamine circuitries in aggression

Yamaguchi, T., Lin, D. 

Current Opinion In Behavioral Sciences.  2018 July 3.  [PDF


A Hypothalamic Midbrain Pathway Essential for Driving Maternal Behaviors.

Fang, Y., Yamaguchi, T., Song, S.C., Tritsch, N.X.,  Lin, D. 

Neuron.  2018 Apr 4.  [PDF] [Supplement]


Ventromedial Hypothalamus and the Generation of Aggression. 

Hashikawa, Y., Hashikawa, K., Falkner, A.L., Lin, D. 

Frontiers in Systems Neuroscience.  2017 Dec 20.  [PDF


Esr1+ cells in the ventromedial hypothalamus control female aggression.  

Hashikawa, K., Hashikawa, Y., Tremblay, R., Zhang, J., Feng, J.E., Sabol, A., Piper, W.T., Lee, H., Rudy, B., Lin, D. 

Nature Neuroscience.  2017 Sep 18.  [PDF] [Supplement]



Hypothalamic control of male aggression-seeking behavior

Falkner, A.L., Grosenick, L., Davidson, T.J., Deisseroth, K., Lin, D. 

Nature Neuroscience.  2016 Apr;19(4):596-604.  [PDF] [Supplement]


Effective modulation of male aggression through lateral septum to medial hypothalamus projection

Wong, L.C., Wang, L., D’amour, J.A., Yumita, T., Chen, G., Yamaguchi, T., Chang, B., Bernstein, H., You, X., Feng, J.E., Froemke, R.C., Lin, D.

Current Biology.  2016 Mar 7;26(5):593-604.  [PDF] [Supplement]


The neural circuits of mating and fighting in male mice

Hashikawa, K., Hashikawa, Y., Falkner, A.L., Lin, D. 

Current Opinion In Neurobiology. 2016 Jun; 38:27-37.  [PDF



Collateral Pathways from the Ventromedial Hypothalamus Mediate Defensive Behaviors.

Wang, L., Chen, I.Z., Lin, D. 

Neuron. 2015 Mar 18;85(6):1344-58.  [PDF] [Supplement]


Recent advances in understanding the role of the hypothalamic circuit during aggression.

Falkner, A.L., Lin, D. 

Frontiers In Systems Neuroscience. 2014 Sep 25;8:168.  [PDF]



Decoding ventromedial hypothalamic neural activity during male mouse aggression.

Falkner, A.L., Dollar, P., Perona, P., Anderson, D.J., Lin, D. 

Journal of Neuroscience. 2014 Apr 23;34(17):5971-84.  [PDF]


Functional identification of an aggression locus in the mouse hypothalamus. 

Lin, D., Boyle, M.P., Dollar, P., Lee, H., Perona, P., Lein, E.S., Anderson, D.J. 

Nature. 2011 Feb 10;470(7333):221-6. [PDF]


Representation of natural stimuli in the mouse main olfactory bulb

Lin, D., Shea, S.D., Katz, L.C. 

Neuron. 2006 Jun 15;50(6):937-49. [PDF] [Supplement]


Encoding social signals in the mouse main olfactory bulb

Lin, D., Zhang, S.Z., Block, E., Katz, L.C. 

Nature. 2005 Mar 24;434(7032):470-7. [PDF]


Molecular determinants of synapsin targeting to presynaptic terminals.

Gitler, D., Xu, Y., Kao, H.T., Lin, D., Lim, S., Feng, J., Greengard, P., Augustine, G.J.

Journal of Neuroscience. 2004 Apr 7;24(14):3711-20. [PDF]


Alpha-2 macroglobulin I1000 V polymorphism in Chinese sporadic Alzheimer's disease and Parkinson's disease. 

Tang, G., Zhang, M., Xie, H., Jiang, S., Wang, Z., Xu, L., Hao, Y., Lin, D., Lan, H., Wang, Y,, Chen, L., Ren, D. (2002)

Neuroscience Letter. 2002 Aug 9;328(2):195-7. 


Genetic study of apolipoprotein E gene, alpha-1 antichymotrypsin gene in sporadic Parkinson disease.

Tang, G., Xie, H., Xu, L., Hao, Y., Lin, D., Ren, D.

Am J Med Genet. 2002 May 8;114(4):446-9.

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